What is Mediastinal Tumors

Mediastinal tumors are abnormal growths that form in the mediastinum, the central part of the chest cavity that lies between the lungs. This area contains vital structures, including the heart, esophagus, trachea, and major blood vessels. Tumors in this region can be benign (non-cancerous) or malignant (cancerous), and their impact on health can vary widely.

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What is Mediastinum?

The mediastinum (from Medieval Latin mediastinus, "midway" is the central compartment of the chest cavity surrounded by loose connective tissue that separates the two lungs from each other. It contains several major structures like the heart and its vessels, the esophagus (food pipe), the trachea (wind pipe), the thymus gland and the lymph nodes of the central chest.

The Mediastinum is divided into three compartments

1. Anterior Mediastinum

Contains the thymus gland, Lymph nodes, Fat

2. Middle Mediastinum

Heart and its covering pericardium, Major Blood Vessels, The Division of the wind pipe i.e. Tracheal bifurcation

3. Posterior Mediastinum

The food pipe (Esophagus), The descending part of the major blood vessel aorta, Many Nerves like the vagus and splanchnic nerves and some lymph glands.

What are the symptoms of Mediastinal Tumors?

As much as 40 % of patients with mediastinal tumours have no symptoms. Frequently these growths are detected on a chest xray performed for another reason. When symptoms are present they are usually due to the pressure that the tumour puts on adjacent structures such as the the spinal cord, heart or the pericardium.

These may include

  • Cough
  • Shortness of breath
  • Chest pain
  • Fever
  • Chills
  • Night sweats
  • Coughing up blood
  • Hoarseness
  • Unexplained weight loss
  • Lymphadenopathy (swollen or tender lymph nodes)
  • Wheezing
  • Stridor (high-pitched and noisy breathing, which could mean a blockage)
  • Eye issues (drooping eyelid, small pupil) on one side of the face

How is a mediastinal tumor diagnosed?

  • Blood tests
  • Chest X-ray
  • Ultrasound
  • Computed tomography (CT) with an IV contrast agent
  • Magnetic resonance imaging (MRI) of the chest
  • Needle biopsy or aspiration or CT-guided needle biopsy
  • Esophagoscopy
  • Bronchoscopy
  • Mediastinoscopy

How are mediastinal tumors treated?

The treatment depends on the type of tumor and its location:

  • Thymic Tumours require surgical removal (click here to know more)
  • Lymphomas are mainly treated with chemotherapy and may be followed by radiation. However surgery may be required to obtain tissue form the tumour for diagnosis.
  • Neurogenic tumors found in the posterior (back) mediastinum are treated surgically.
  • Minimally Invasive Surgery for Mediastinal Tumours (Thoracoscopy / VATS) In past open surgery through a large cut in the chest either on the breast bone (Sternotomy) or on the side of chest (thoracotomy) was the only way to treat these tumours wherever surgery was required. But in todays era many of these tumours can be operated via small key hole incision by Thoracoscopy/ VATS or by using the state of art Robotic Surgery.

    Click here to know more about Thoracoscopy/ VATS

    Click here to know more about Robotic Surgery

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